Generation, Characterisation and Application of Nanostructured LLC-Gels


Gelled complex fluids

Lyotropic Liquid Crystal Gels (LCC-Gels) are a special case of complex fluids that are of interest for biomedical applications such as tissue healing applications and (trans-)dermal drug delivery systems. The gel network provides mechanical stability, while the entrapped LLC nanostructures provide an additional function, e.g. as reservoir for drugs of different polarities. LLC-Gels can be obtain either by adding a gelator to a complex fluid or by replacing the solvent of a gel by a complex fluid. If the two structures, i.e. the gel network and the complex fluid, form simultaneously but independently, the system is called “orthogonal self-assembled sytem”. [1]

In this research the focus will be on non-irritating, bio-compatible gels. To achieve the formulation of those gels, binary systems consisting of water and sugar-based surfactants which form hexagonal (H1) and lamellar (Lα) LLCs will be gelated according to previous studies [2]. The gelators are low molecular weight gelators (LMWGs), which self-assemble reversibly into fibrillar networks and are biodegradable. The present work seeks to (a) determine whether the gelled LLC phase is an orthogonal self-assembled system; (b) adjust the rheological behaviour via the gelator concentration, the type of lyotropic LC phase, or an alignment of fibres; (c) align gel fibres by growing them in an external field or in an anisotropic matrix (H1 or Lα).

[1] C. Stubenrauch, F. Gießelmann, Angew. Chem. Int. Ed. 201655, 3268-3275.

[2] K. Steck, S. Dieterich, C. Stubenrauch, F. Giesselmann, J. Mater. Chem. C 2020, 8, 5335-5348.

This image shows Philomène  Le Bastart de Villeneuve

Philomène Le Bastart de Villeneuve


PhD Student

This image shows Cosima Stubenrauch

Cosima Stubenrauch

Prof. Dr.

Dean of Faculty

To the top of the page